Mast Cell Activation Syndrome (MCAS) can lead to a wide range of symptoms that can affect various organ systems. These symptoms can vary from person to person and may be mild or severe.
Skin Symptoms: Itching (pruritus), flushing or redness of the skin. hives (urticaria). swelling (angioedema), rashes.
Gastrointestinal Symptoms: Abdominal pain or cramping, diarrhea, nausea and vomiting, gastroesophageal reflux (GERD), food intolerances or sensitivities.
Respiratory Symptoms: Wheezing, shortness of breath, coughing, congestion, sinus symptoms.
Cardiovascular Symptoms: Rapid or irregular heartbeat (tachycardia, arrhythmias), low blood pressure (hypotension), fainting or near-fainting (syncope).
Neurological Symptoms: Headaches, migraines, brain fog, cognitive impairment, dizziness, anxiety, panic attacks, neuropathic pain.
Musculoskeletal Symptoms: Joint pain (arthralgia), muscle pain (myalgia), bone pain, weakness.
Urological Symptoms: Frequent urination, painful urination, interstitial cystitis-like symptoms.
Endocrine and Autonomic Symptoms: Fatigue, insomnia, temperature dysregulation (feeling too hot or too cold), sweating, weight fluctuations.
Allergic Reactions: Anaphylaxis (severe and potentially life-threatening allergic reaction), increased sensitivity to allergens and other triggers